1.详细询问病史，包括发病缓慢、病程长短和进展，以及是否患有甲状腺免疫性眼眶病（TRID）或鼻窦病，是否有外伤等全身性疾病。并注意疼痛和进展。
2、检查眼球突出、触诊、搏动、眶周等变化。
3.影像学检查包括眼眶和头部X超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声、超声CT扫描和磁共振成像（MRI）。
4.病理检查。
5.甲状腺功能检查、癌胚抗原检查、血常规检查等实验室检查。
